Новинки Сиддхартхи Мукерджи

Эта эпохальная книга — всеобъемлющая, живо изложенная и глубоко обоснованная научно история отношений человечества и рака, на фоне которой разворачиваются личные истории войны с «царем всех болезней». Проводя читателя через изменчивые представления об этой болезни в разные эпохи, способы лечения, вехи познания ее механизмов и конфликты интересов вокруг нее, автор раскрывает причины ограниченности побед над ней и намечает реалистичные контуры сосуществования с ней в будущем. Извечным мечтам о волшебной пилюле от рака на страницах книги противостоит враг, столь коварный потому, что слишком напоминает в своем биологическом совершенстве искаженные отражения нас самих.

Перед читателем три взаимопроникающие биографии: идеи гена, человеческого общества в ходе ее разработки и семьи автора, в которую эта идея проникла с багажом наследственного психического заболевания. На страницах этой эпохальной книги концепция гена зарождается в смутных догадках Аристотеля об информационной природе наследственности и в представлениях Парацельса о гомункулах, вплетается в образы людей, создававших генетику в XIX–XX веках, вовлекается в евгенические проекты и эволюционирует в технологии редактирования геномов. Наблюдая влияние генов на клеточные и человеческие судьбы как ученый и врач, чью собственную семью преследует наследственный недуг, Мукерджи пропитывает научную историю драмами людей с генетическими болезнями и обозначает этические вызовы, с которыми мы столкнулись, научившись “читать” и “писать” на языке ДНК.

The Gene is the story of one of the most powerful and dangerous ideas in our history from the author of The Emperor of All Maladies.
The story begins in an Augustinian abbey in 1856, and takes the reader from Darwin’s groundbreaking theory of evolution, to the horrors of Nazi eugenics, to present day and beyond - as we learn to “read” and “write” the human genome that unleashes the potential to change the fates and identities of our children.
Majestic in its scope and ambition, The Gene provides us with a definitive account of the epic history of the quest to decipher the master-code that makes and defines humans – and paints a fascinating vision of both humanity’s past and future.
For fans of Sapiens by Yuval Noah Harari, A Brief History of Time by Stephen Hawking and Being Mortal by Atul Gwande.

Чи є в медицині закони, аналогічні до інших наук? Автор розповідає про найзагадковіші та найповчальніші випадки зі свого досвіду, які врешті-решт привели його до визначення трьох принципів, що керують сучасною медициною. Ця книжка, багата на історичні факти й приклади з життя, показує нам захопливий світ, у якому лікарі ведуть боротьбу та здійснюють відкриття і який рідко постає перед широким загалом. "Закони медицини", провокативні й людяні, є дороговказом для кожної професії, у якій є місце для відкриття. Зрештою, ця книжка закладає підвалини нового розуміння не лише медицини, а й світу навколо.

Вражаюча розповідь про найважливішу науку сучасності — генетику. Справжня біографія генів від знаменитого фахівця з біології Сіддгартха Мукерджі. Як розшифрувати людський геном? Коли ми зможемо «читати» і «переписувати» генетичну інформацію? Як гени впливають на долю людини? Захоплива історія про спадковість та вплив генів на вибір життєвого шляху для особистості. Книга — для всіх, хто цікавиться майбутнім людства.

На страницах этой эпохальной книги концепция гена только зарождается Перед читателем три взаимопроникающие биографии: идеи гена, человеческого общества в ходе ее разработки и семьи автора, в которую эта идея проникла с багажом наследственного психического заболевания. На страницах этой эпохальной книги концепция гена зарождается в смутных догадках Аристотеля об информационной природе наследственности и в представлениях Парацельса о гомункулах, вплетается в образы людей, создававших генетику в XIX–XX веках, вовлекается в евгенические проекты и эволюционирует в технологии редактирования геномов. Наблюдая влияние генов на клеточные и…

На страницах этой эпохальной книги концепция гена только зарождается Перед читателем три взаимопроникающие биографии: идеи гена, человеческого общества в ходе ее разработки и семьи автора, в которую эта идея проникла с багажом наследственного психического заболевания. На страницах этой эпохальной книги концепция гена зарождается в смутных догадках Аристотеля об информационной природе наследственности и в представлениях Парацельса о гомункулах, вплетается в образы людей, создававших генетику в XIX–XX веках, вовлекается в евгенические проекты и эволюционирует в технологии редактирования геномов. Наблюдая влияние генов на клеточные и человеческие судьбы как ученый и врач, чью собственную семью преследует наследственный недуг, Мукерджи пропитывает научную историю драмами людей с генетическими болезнями и обозначает этические вызовы, с которыми мы столкнулись, научившись “читать” и “писать” на языке ДНК. © 2016, Siddhartha Mukherjee All rights reserved © Joan Mir?, Bleu I, 1961 © Successi? Mir? / УПРАВИС, 2023 © К. Сайфулина, О. Волкова (посл. глава части II, эпилог, благодарности, словарь терминов, хронология, примечания), перевод на русский язык, 2023 © А. Бондаренко, художественное оформление, макет, 2023 © ООО “Издательство Аст ”, 2023 Издательство CORPUS ®

The Gene is the story of one of the most powerful and dangerous ideas in our history from the author of The Emperor of All Maladies.

The story begins in an Augustinian abbey in 1856, and takes the reader from Darwin’s groundbreaking theory of evolution, to the horrors of Nazi eugenics, to present day and beyond - as we learn to “read” and “write” the human genome that unleashes the potential to change the fates and identities of our children.

Majestic in its scope and ambition, The Gene provides us with a definitive account of the epic history of the quest to decipher the master-code that makes and defines humans – and paints a fascinating vision of both humanity’s past and future.

The Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee.

Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function.

The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856 where a monk stumbles on the idea of a ‘unit of heredity’. It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.

This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.

Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

From the Pulitzer Prize-winning, bestselling author of The Emperor of All Maladies—a magnificent history of the gene and a response to the defining question of the future: What becomes of being human when we learn to “read” and “write” our own genetic information? Siddhartha Mukherjee has a written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising…

Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all.

Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences?

Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine.

Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all.

Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences?

Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine.

Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

Ця книжка - історія раку. Це літопис давньої хвороби - колись таємничої, "нашептпної", яка переродилась у смертоносну мінливу річ, наділену такою всеохопною метафоричною могутністю в медицині, науці та політиці, що її часто називають справжньою чумою нашого покоління. Ця книжка - біографічна в прямому розумінні цього слова, спроба проникнути у свідомість цієї безсмертної недуги, зрозуміти її особистість, зняти покрив таємничности з її поведінки. Але моя головна мета - поставити питання поза біографією: чи можна припустити, що в прийдешності настане кінець раку? Чи вдасться назавжди викоренити цю хворобу з наших тіл і з суспільства?

Книга "Царь всех болезней. Биография рака" переведена на 33 языка и удостоена:
- пулитцеровской премии;
- премии Пен-клуба как лучшее научно-популярное произведение;
- премии за исследования в области онкологии;
- премии "New York Times" как лучшая книга 2010 года;
- премии журнала "Time" как лучшая книга 2010 года.
Номинирована на:
- книжную премию "Los Angeles Times";
- национальную премию литературных критиков США.

In The Emperor of All Maladies, Siddhartha Mukherjee, doctor, researcher and award-winning science writer, examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years.
The story of cancer is a story of human ingenuity, resilience and perseverance, but also of hubris, arrogance and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out ‘war against cancer’. Mukherjee recounts centuries of discoveries, setbacks, victories and deaths, told through the eyes of predecessors and peers, training their wits against an infinitely resourceful adversary.
From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteeth-century recipient of primitive radiation and chemotherapy and Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through toxic, bruising, and draining regimes to survive and to increase the store of human knowledge.
Riveting and magesterial, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments and a brilliant new perspective on the way doctors, scientists, philosophers and lay people have observed and understood the human body for millennia.

Winner of the Guardian First Book Award 2011Winner of the Pulitzer Prize for Non-fiction 2011Shortlisted for the Wellcome Trust Book PrizeShortlisted for the Duff Cooper PrizeNow, as cancer becomes an ever more universal experience, the need to understand it, and its treatment, has never been more compelling. In this groundbreaking and award-winning account Siddhartha Mukherjee tells the fascinating story of our relationship with this disease. From brutal early surgical treatments, to Sidney Farber’s hugely risky discovery of chemotherapy, to the author’s treatment of his own patients, he reveals how far we have come in solving one of science's great mysteries and offers a fascinating glimpse of our future progress.

The Emperor of All Maladies is a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.